Vigilant Vector: Heart-Specific Promoter in an Adeno-Associated Virus Vector for Cardioprotection
نویسندگان
چکیده
منابع مشابه
Vigilant vector: heart-specific promoter in an adeno-associated virus vector for cardioprotection.
Repeated bouts of ischemia in the heart lead to fibrosis and eventually to heart failure. Although certain genes, such as SOD or hemoxygenase and antisense to AT(1)R, ACE, and (beta(1)-AR can provide short-term protection of the heart from ischemia, there is no known mechanism for constantly responding to repeated incidences of ischemia. We hypothesized that a "vigilant vector," designed to be ...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2002
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hy0202.103472